External Validation of Predictors of Mortality in Polytrauma Patients
- Population
- Adult Level I trauma activations
- Evidence
- Retrospective external validation
- Next milestone
- Prospective workflow evaluation
Clinical intelligence for critical care
Bring your patient’s trajectory into view.
Clinical intelligence to help care teams understand a patient’s changing condition and hospital leaders improve care across the service line.
ACTIVATE is our EHR-integrated clinical intelligence platform for trauma and critical care. It brings the patient’s changing risk and clinical context into the workflow, so care teams can follow each patient’s course over time.
Behind every changing signal is a patient whose story is still unfolding. ACTIVATE helps care teams see where that story is headed.
Understand the course of this patient’s care.
- 01
Trajectory
How is the patient changing?
- 02
Contributing factors
What is shaping that change?
- 03
Shared context
What does the care team need to see together?
Follow changing risk across the patient and the unit.
ACTIVATE brings patient context and risk trajectories into EHR workflows.
Care teams can examine an individual patient’s course and review changing signals across the unit.
Published trauma research provides the starting point. Additional critical-care capabilities are in development around the same shared patient view.
As additional capabilities are validated, they should help teams investigate more aspects of the patient’s course within the same clinical workflow. Hospitals can build on their experience with ACTIVATE as they address additional critical-care needs.
Review our published trauma researchAvailable for deployment
Trauma mortality
In development
Unplanned ICU admission, trauma-specific frailty, pulmonary embolism, severe sepsis, and surgical-site infection.
Planned for ACTIVATE
Clinical intelligence that knows what to look for.
Understanding a patient means knowing which details matter as their condition changes.
We are developing ACTIVATE to bring the patient’s evolving story into view and help the team investigate what deserves attention. Trauma and critical-care expertise shapes which details come forward and which questions remain unresolved.
The aim is to help the team examine the patient’s course with the relevant evidence in front of them.
Scale clinical AI faster.
Once ACTIVATE is connected to your EHR, new clinical capabilities can build on that same integration.
Our team develops those capabilities around critical-care workflows, with clinicians guiding their fit for local use.
ACTIVATE provides the bedside foundation. Our planned quality intelligence product extends learning across patients.
Deploy
Introduce a locally evaluated capability into clinical use.
Scale
Add capabilities through the existing clinical data connection.
Innovate
Let clinical questions and reviewed findings shape what comes next.
Planned quality intelligence product
Learn from the course of care across patients.
For clinical and operational leaders across the critical-care service line.
Some questions begin with one patient and lead to many others.
When a patient returns unexpectedly to intensive care, leaders need to understand what preceded that return. They also need to know whether similar patients are following a similar course, and what that suggests about their care.
Teams must reconstruct encounters and compare patient groups. Daily demands can leave little time for that investigation.
Our planned quality intelligence product extends this perspective across the critical-care service line. Built on the clinical data foundation established through ACTIVATE, it will help leaders investigate questions across patients and surface emerging patterns for review.
The purpose is to help clinical leaders decide what to change in care, then examine whether those changes are helping.
From findings to changes in care
- Investigate patterns. The quality product helps leaders examine questions across patients.
- Decide what to change. Clinical leaders review the findings and decide whether protocols or pathways should change.
- Apply approved changes. Hospital teams use their existing clinical processes.
- Assess the results. Subsequent analysis helps leaders evaluate what happens in patient care.
An innovation flywheel for critical care.
Our clinical collaborators help identify important problems and evaluate whether new capabilities are useful in practice. Their work informs what we develop next and the evidence needed before clinical use.
Our published research begins in trauma. We are building on that foundation as ACTIVATE expands toward broader critical care.
Meet the people behind ACTIVATEResearch questionDefine the clinical question and evidence threshold
Study designAlign the cohort, outcomes, and evaluation plan
EvaluationAssess model behavior locally or across participating centers
Evidence generationDocument findings and define the next research milestone
Understand how each model performs in your clinical setting.
ACTIVATE supports evaluation with your hospital’s data before a model enters clinical use.
Clinical and governance leaders guide its introduction and review its performance over time.
- 01
Connect
Map relevant EHR data already captured in clinical workflows.
- 02
Validate locally
Evaluate model performance on relevant local patient populations.
- 03
Evaluate before clinical use
Assess model behavior and workflow fit through silent evaluation.
- 04
Introduce
Configure access and presentation with clinical and governance leaders.
- 05
Govern
Monitor performance and document changes and review decisions over time.
Health systems can also use this process to evaluate and govern models they develop or select.
Peer-reviewed research
Our clinical evidence begins in trauma.
TraumaCare.AI co-authored a 2024 Journal of Surgical Research study of mortality predictors in approximately 5,000 adult Level I trauma activations at the University of Cincinnati.
The study externally evaluated previously published predictors and developed an institution-specific model using local data. That retrospective work provides the evidence foundation from which ACTIVATE’s trauma mortality capability has evolved.
Scope
Review the evidenceIt does not establish prospective clinical impact or validation across broader critical-care populations.
Start with the problem your team needs to solve.
Tell us about the clinical questions your care teams face, or the patterns your service-line leaders need to understand.
Explore ACTIVATE for bedside clinical intelligence, or discuss the quality investigations your organization needs better tools to pursue.
Request a working session
Please do not include patient information.